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Peroxiredoxin-4 Recombinant Protein

Product Specifications

Background

Peroxiredoxin-4 (PRDX4) is a member of the AhpC/TSA family. PRDX4 is a cytoplasmic protein and contains one thioredoxin domain. PRDX4 exists in homodimer or heterodimer with PRDX1. PRDX4 reduces hydrogen peroxide and alkyl hydroperoxides to water and alcohol with the use of reducing equivalents derived from thiol-containing donor molecules. In addition, PRDX4 is probably involved in redox regulation of the cell, regulating the activation of NF-kappa-B in the cytosol by a modulation of I-kappa-B-alpha phosphorylation.

CAS Number

9000-83-3

NCBI Gene ID

10549

Swiss Prot

Q13162

Accession Number

Q13162

Tag

N-6 His tag

Type

Recombinant Proteins

Source

E. coli

Field of Research

Cancer, Cell Cycle, Signal Transduction, Other

Buffer

Supplied as a 0.2 um filtered solution of 20mM PB, 150mM NaCl, 1mM DTT, pH 7.2. It is not recommended to reconstitute to a concentration less than 100 ug/ml.

Shipping Conditions

Dry Ice

Calculated Molecular Weight

33.8 kD

Applications Notes

This recombinant protein can be used for biological assays. For research use only.

NCBI Official Name

Peroxiredoxin 4

NCBI Organism

Homo sapiens

Other Product Names

Peroxiredoxin-4, Antioxidant Enzyme AOE372, AOE37-2, Peroxiredoxin IV, Prx-IV, Thioredoxin Peroxidase AO372, Thioredoxin-Dependent Peroxide Reductase A0372, PRDX4

Species

Human

Protein ID

767904139

Physical Properties

Liquid

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