PPIase H Recombinant Protein
Product Specifications
Background
Peptidyl-Prolyl Cis-Trans Isomerase H (PPIH) belongs to the Cyclophilin-type PPIase family that accelerate the folding of proteins. PPIases can catalyze the cis-trans isomerization of Proline Imidic peptide bonds in oligopeptides. PPIH participates in pre-mRNA splicing. It is a specific component of the complex that includes pre-mRNA processing factors PRPF3, PRPF4, and PRPF18, as well as U4/U5/U6 tri-snRNP. In addition, PPIH has PPIase activity and may play a role as a chaperone mediating the interactions between different proteins inside the spliceosome.
NCBI Gene ID
10465
Swiss Prot
O43447
Accession Number
O43447
Tag
N-6 His tag
Type
Recombinant Proteins
Source
E. coli
Field of Research
Other
Buffer
Supplied as a 0.2 um filtered solution of 20mM PB, 150mM NaCl, pH 7.2. It is not recommended to reconstitute to a concentration less than 100 ug/ml.
Shipping Conditions
Dry Ice
Product Datasheet
https://www.prosci-inc.com/?datasheet_sku=91-233
Calculated Molecular Weight
21.4 kD
Applications Notes
This recombinant protein can be used for biological assays. For research use only.
NCBI Official Name
Peptidylprolyl isomerase H
NCBI Organism
Homo sapiens
Other Product Names
Peptidyl-Prolyl Cis-Trans Isomerase H, PPIase H, Rotamase H, Small Nuclear Ribonucleoprotein Particle-Specific Cyclophilin H, CypH, U-snRNP-Associated Cyclophilin SnuCyp-20, USA-CYP, PPIH, CYP20
Species
Human
Physical Properties
Liquid
CAS Number
9000-83-3
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