Protein disulfide-isomerase A3 Recombinant Protein
Product Specifications
Background
PDIA3 protein is also known as Protein disulfide-isomerase A3. It is a protein that in humans is encoded by the PDIA3 gene.PDIA3 is an enzyme that belongs to the endoplasmic reticulum and interacts with lectin chaperones calreticulin and calnexin to modulate folding of newly synthesized glycoproteins. PDIA3 interacts with thiazide-sensitive sodium-chloride cotransporter in the kidney and is induced by glucose deprivation. PDIA3 is part of the major histocompatibility complex (MHC) class I peptide-loading complex (TAP1), which is important for formation of the final antigen conformation and export from the endoplasmic reticulum to the cell surface.
CAS Number
9000-83-3
NCBI Gene ID
281803
Swiss Prot
A5D7E8
Accession Number
A5D7E8
Tag
C-6 His tag
Type
Recombinant Proteins
Source
Human Cells
Buffer
Supplied as a 0.2 um filtered solution of 20mM TrisHCl,150mM NaCl,10%Glycerol, pH7.5. It is not recommended to reconstitute to a concentration less than 100 ug/ml.
Shipping Conditions
Dry Ice
Calculated Molecular Weight
55.3 kD
Applications Notes
This recombinant protein can be used for biological assays. For research use only.
NCBI Official Name
Protein disulfide isomerase family A member 3
NCBI Organism
Bos taurus
Other Product Names
PDIA3 protein, Protein disulfide-isomerase A3, 58 kDa glucose-regulated protein, Disulfide isomerase ER-60, ER protein 57, PDIA3
Species
Human
Physical Properties
Liquid
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