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Protein disulfide-isomerase A3 Recombinant Protein

Product Specifications

Background

PDIA3 protein is also known as Protein disulfide-isomerase A3. It is a protein that in humans is encoded by the PDIA3 gene.PDIA3 is an enzyme that belongs to the endoplasmic reticulum and interacts with lectin chaperones calreticulin and calnexin to modulate folding of newly synthesized glycoproteins. PDIA3 interacts with thiazide-sensitive sodium-chloride cotransporter in the kidney and is induced by glucose deprivation. PDIA3 is part of the major histocompatibility complex (MHC) class I peptide-loading complex (TAP1), which is important for formation of the final antigen conformation and export from the endoplasmic reticulum to the cell surface.

CAS Number

9000-83-3

NCBI Gene ID

281803

Swiss Prot

A5D7E8

Accession Number

A5D7E8

Tag

C-6 His tag

Type

Recombinant Proteins

Source

Human Cells

Buffer

Supplied as a 0.2 um filtered solution of 20mM TrisHCl,150mM NaCl,10%Glycerol, pH7.5. It is not recommended to reconstitute to a concentration less than 100 ug/ml.

Shipping Conditions

Dry Ice

Calculated Molecular Weight

55.3 kD

Applications Notes

This recombinant protein can be used for biological assays. For research use only.

NCBI Official Name

Protein disulfide isomerase family A member 3

NCBI Organism

Bos taurus

Other Product Names

PDIA3 protein, Protein disulfide-isomerase A3, 58 kDa glucose-regulated protein, Disulfide isomerase ER-60, ER protein 57, PDIA3

Species

Human

Physical Properties

Liquid

Frequently Asked Questions

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