OX40 Recombinant Protein
Product Specifications
Background
OX40 binds to receptors on T-cells, preventing them from dying and subsequently increasing cytokine production. OX40 has a critical role in the maintenance of an immune response. OX40:Fc was shown to prevent OX40 from reaching the T-cell receptors, thus reducing the T-cell response. Experiments in mice have demonstrated that OX40:Fc can reduce the symptoms associated with the cytokine storm (an immune overreaction) while allowing the immune system to fight off the virus successfully.
CAS Number
9000-83-3
NCBI Gene ID
7293
Swiss Prot
O75888
Accession Number
P43489
Tag
Fc Tag
Type
Recombinant Proteins
Source
HEK293 cells
Concentration
1mg/ml after reconstitution.
Buffer
Contains PBS. Reconstitute with 50 μ l sterile water.
Shipping Conditions
Room Temp
Storage Conditions
Stable for at least 6 months after receipt when stored at -20˚ C.
Applications Notes
This recombinant proteins is for research use only.
NCBI Official Name
Tumor necrosis factor receptor superfamily member 4
NCBI Organism
Homo sapiens
Other Product Names
TNFRSF 4, Tumor Necrosis Factor Receptor Superfamily Member 4, CD134
Species
Human, Mouse
Protein ID
1171933
Physical Properties
Lyophilized
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