Sulfamidase Recombinant Protein
Product Specifications
Background
N-Sulphoglucosamine Sulphohydrolase (SGSH) is an important member of the sulfatase family which is involved in the degradation of heparin sulfate. SGSH binds one calcium ion per subunit as a cofactor. SGSH catalyzes N-sulfo-D-glucosamine and H2O to D-glucosamine and sulfate. SGSH deficiency is result in mucopolysaccharidosis type 3A (MPS3A), a recessive lysosomal storage disease characterized by neurological dysfunction but relatively mild somatic manifestations.
CAS Number
9000-83-3
NCBI Gene ID
6448
Swiss Prot
P51688
Accession Number
P51688
Tag
C-6 His tag
Type
Recombinant Proteins
Source
Human Cells
Field of Research
Neuroscience, Signal Transduction
Buffer
Supplied as a 0.2 um filtered solution of 20mM TrisHCl,150mM NaCl,1mM GaCl2,10%Glycerol, pH7.5. It is not recommended to reconstitute to a concentration less than 100 ug/ml.
Shipping Conditions
Dry Ice
Calculated Molecular Weight
55.72 kD
Applications Notes
This recombinant protein can be used for biological assays. For research use only.
NCBI Official Name
N-sulfoglucosamine sulfohydrolase
NCBI Organism
Homo sapiens
Other Product Names
N-Sulphoglucosamine Sulphohydrolase, Sulfoglucosamine Sulfamidase, Sulphamidase, SGSH, HSS
Species
Human
Physical Properties
Liquid
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