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Sulfamidase Recombinant Protein

Product Specifications

Background

N-Sulphoglucosamine Sulphohydrolase (SGSH) is an important member of the sulfatase family which is involved in the degradation of heparin sulfate. SGSH binds one calcium ion per subunit as a cofactor. SGSH catalyzes N-sulfo-D-glucosamine and H2O to D-glucosamine and sulfate. SGSH deficiency is result in mucopolysaccharidosis type 3A (MPS3A), a recessive lysosomal storage disease characterized by neurological dysfunction but relatively mild somatic manifestations.

CAS Number

9000-83-3

NCBI Gene ID

6448

Swiss Prot

P51688

Accession Number

P51688

Tag

C-6 His tag

Type

Recombinant Proteins

Source

Human Cells

Field of Research

Neuroscience, Signal Transduction

Buffer

Supplied as a 0.2 um filtered solution of 20mM TrisHCl,150mM NaCl,1mM GaCl2,10%Glycerol, pH7.5. It is not recommended to reconstitute to a concentration less than 100 ug/ml.

Shipping Conditions

Dry Ice

Calculated Molecular Weight

55.72 kD

Applications Notes

This recombinant protein can be used for biological assays. For research use only.

NCBI Official Name

N-sulfoglucosamine sulfohydrolase

NCBI Organism

Homo sapiens

Other Product Names

N-Sulphoglucosamine Sulphohydrolase, Sulfoglucosamine Sulfamidase, Sulphamidase, SGSH, HSS

Species

Human

Physical Properties

Liquid

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