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Notch1 Recombinant Protein

Product Specifications

Background

Notch signaling pathway regulates many different cell fate decisions in both vertebrate and invertebrate species. There are 5 canonical Notch ligands in mammals: Jagged-1, Jagged-2, DLL1, DLL3 and DLL4. These can bind to the four Notch receptors Notch 1-4. It is important for pattern formation during development such as neurogenesis, angiogenesis or myogenesis and regulates T cell development and stem cell maintenance. Notch signaling is also involved in cellular processes through-out adulthood. Signaling via Notch occurs between neighbouring cells and both the receptor and its ligands are transmembrane proteins.

CAS Number

9000-83-3

NCBI Gene ID

18128

Swiss Prot

P48023

Accession Number

Q01705

Tag

Fc Tag

Type

Recombinant Proteins

Source

CHO cells

Concentration

1mg/ml after reconstitution.

Buffer

Contains PBS. Reconstitute with 50 μ l sterile water.

Shipping Conditions

Room Temp

Storage Conditions

Stable for at least 6 months after receipt when stored at -20˚ C.

Applications Notes

This recombinant proteins is for research use only.

NCBI Official Name

Notch 1

NCBI Organism

Mus musculus

Other Product Names

Neurogenic Locus Notch Homolog Protein 1, Motch A, mT14, p300

Species

Mouse

Protein ID

384872684

Physical Properties

Lyophilized

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