NgR Recombinant Protein
Product Specifications
Background
Nogo Receptor (NgR) is a glycosylphosphoinositol (GPI) -anchored protein that belongs to the Nogo recptor family. Human NgR is predominantly expressed in neurons and their axons in the central nervous systems. As a receptor for myelin-derived proteins Nogo, myelin-associated glycoprotein (MAG) and myelin oligodendrocyte glycoprotein (OMG), NgR mediates axonal growth inhibition and may play a role in regulating axonal regeneration and plasticity in the adult central nervous system. NgR may be proposed as a potential drug target for treatment of various neurological conditions. Additionally, NgR may play a role in regulating the function of gap junctions.
CAS Number
9000-83-3
NCBI Gene ID
65078
Swiss Prot
Q9BZR6
Accession Number
Q9BZR6
Tag
C-6 His tag
Type
Recombinant Proteins
Source
Human Cells
Field of Research
Cancer
Buffer
Lyophilized from a 0.2 um filtered solution of 20mM PB, 150mM NaCl, pH 7.4. It is not recommended to reconstitute to a concentration less than 100 ug/ml. Dissolve the lyophilized protein in ddH2O.
Shipping Conditions
Room Temp
Calculated Molecular Weight
46.32 kD
Applications Notes
This recombinant protein can be used for biological assays. For research use only.
NCBI Official Name
Reticulon 4 receptor
NCBI Organism
Homo sapiens
Other Product Names
Reticulon-4 Receptor, Nogo Receptor, NgR, Nogo-66 Receptor, RTN4R, NOGOR
Species
Human
Physical Properties
Lyophilized
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