Nampt Recombinant Protein
Product Specifications
Background
Nicotinamide phosphoribosyltransferase (Nampt; pre-B cell colony-enhancing factor; PBEF; Visfatin) is an 52kDa adipokine secreted by adipose tissue and involved in the biosynthesis of nicotinamide adenine dinucleotide (NAD+) . Two forms of Nampt exist, an intracellular form (iNampt) and an extracellular form (eNampt) . While the function of iNampt as an essential and rate-limiting NAD+ biosynthetic enzyme is well established, the physiological role of eNampt is still a matter of debate. Nampt has various functions, including the promotion of vascular smooth muscle cell maturation and inhibition of neutrophil apoptosis. It activates insulin receptor and has insulin-mimetic effects, lowering blood glucose and improving insulin sensitivity. The protein is highly expressed in visceral fat and serum levels of the protein correlate with obesity.
NCBI Gene ID
297508
Swiss Prot
P04916
Accession Number
Q80Z29
Tag
DDDDK Tag
Type
Recombinant Proteins
Source
HEK293 cells
Field of Research
Cancer, Obesity
Concentration
0.35mg/ml
Buffer
0.2um-filtered solution in PBS, pH 7.2.
Shipping Conditions
Blue Ice
Storage Conditions
Working aliquots are stable for up to 3 months when stored at -20˚ C.
Product Datasheet
https://www.prosci-inc.com/?datasheet_sku=90-053
Applications Notes
This recombinant proteins is for research use only.
NCBI Official Name
Nicotinamide phosphoribosyltransferase
NCBI Organism
Rattus norvegicus
Other Product Names
Pre-B Cell Colony Enhancing Factor 1, PBEF1, Nicotinamide Phosphoribosyltransferase
Species
Rat
Protein ID
68565643
Physical Properties
Liquid
CAS Number
9000-83-3
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