NHP2L1 Recombinant Protein
Product Specifications
Background
NHP2-Like Protein 1 (NHP2L1) is a member of the ribosomal protein L7Ae family. NHP2L1 proteinis limited to the nucleus, primarily focused in the dense fibrillar component of the nucleolus. NHP2L1 has been shown to interact with RAD17and PRPF31. The protein undergoes a conformational change upon RNA-binding. NHP2L1 binds to the 5-stem-loop of U4 snRNA and may play a role in the late stage of spliceosome assembly, prior to step I of splicing catalysis.
CAS Number
9000-83-3
NCBI Gene ID
4809
Swiss Prot
P55769
Accession Number
P55769
Tag
N-6 His tag
Type
Recombinant Proteins
Source
E. coli
Field of Research
Other
Buffer
Lyophilized from a 0.2 um filtered solution of 20mM TrisHCl, 600mM NaCl, pH 8.0. It is not recommended to reconstitute to a concentration less than 100 ug/ml. Dissolve the lyophilized protein in ddH2O.
Shipping Conditions
Room Temp
Calculated Molecular Weight
16.3 kD
Applications Notes
This recombinant protein can be used for biological assays. For research use only.
NCBI Official Name
SNU13 homolog, small nuclear ribonucleoprotein (U4/U6.U5)
NCBI Organism
Homo sapiens
Other Product Names
NHP2-Like Protein 1, High Mobility Group-Like Nuclear Protein 2 Homolog 1, OTK27, SNU13 Homolog, hSNU13, U4/U6.U5 tri-snRNP 15.5 kDa Protein, NHP2L1
Species
Human
Physical Properties
Lyophilized
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