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Neurotrophin-3 Recombinant Protein

Product Specifications

Background

Neurotrophin-3 (NT-3) is a member of the NGF family of neurotrophic factors and is structurally related to beta -NGF, BDNF and NT-4. The NT3 cDNA encodes a 257 amino acid residue precursor protein with a signal peptide and a proprotein that are cleaved to yield the 119 amino acid residue mature NT3.The amino acid sequences of mature human, murine and rat NT-3 are identical. NT-3 selectively promotes the differentiation and survival of specific neuronal subpopulations in both the central as well as the peripheral nervous systems.

CAS Number

9000-83-3

NCBI Gene ID

4908

Swiss Prot

P20783

Accession Number

P20783

Tag

Tag Free

Type

Recombinant Proteins

Source

E. coli

Field of Research

Cell Cycle, Neuroscience, Signal Transduction

Buffer

Lyophilized from a 0.2 um filtered solution of 20mM PB, 250mM NaCl, pH 7.2. It is not recommended to reconstitute to a concentration less than 100 ug/ml. Dissolve the lyophilized protein in ddH2O.

Shipping Conditions

Room Temp

Calculated Molecular Weight

13.6 kD

Applications Notes

This recombinant protein can be used for biological assays. For research use only.

NCBI Official Name

Neurotrophin 3

NCBI Organism

Homo sapiens

Other Product Names

Neurotrophin-3, NT-3, HDNF, Nerve Growth Factor 2, NGF-2, Neurotrophic Factor, NTF3, NT3

Species

Human

Physical Properties

Lyophilized

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