Neurocalcin-delta Recombinant Protein
Product Specifications
Background
Neurocalcin-delta (NCALD) is a neuronal calcium-binding protein that belongs to the neuronal calcium sensor (NCS) family. It expressed in mammalian brains. NCALD contains an N-terminal myristoylation signal and four EF-hand calcium binding loops. The protein possesses a Ca2+ /myristoyl switch. It is cytosolic at resting calcium levels. However, elevated intracellular calcium levels induce a conformational change which exposes the myristoyl group, resulting in protein association with membranes and partial co-localization with the perinuclear trans-golgi network. NCALD protein is thought to be a regulator of G protein-coupled receptor signal transduction.
NCBI Gene ID
83988
Swiss Prot
P61601
Accession Number
P61601
Tag
N-6 His tag
Type
Recombinant Proteins
Source
E. coli
Field of Research
Neuroscience
Buffer
Supplied as a 0.2 um filtered solution of 20mM TrisHCl, 100mM NaCl, 1mM DTT, 40% Glycerol, pH 8.0. It is not recommended to reconstitute to a concentration less than 100 ug/ml.
Shipping Conditions
Dry Ice
Product Datasheet
https://www.prosci-inc.com/?datasheet_sku=91-219
Calculated Molecular Weight
24.4 kD
Applications Notes
This recombinant protein can be used for biological assays. For research use only.
NCBI Official Name
Neurocalcin delta
NCBI Organism
Homo sapiens
Other Product Names
Neurocalcin-Delta, NCALD
Species
Human
Physical Properties
Liquid
CAS Number
9000-83-3
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