SLAMF 4 Recombinant Protein
Product Specifications
Background
Natural killer cell receptor 2B4 is also known as NK cell type I receptor protein 2B4 (NKR2B4 or h2B4), SLAM family member 4 (SLAMF4), Signaling lymphocytic activation molecule 4, CD antigen CD244. NKR2B4 / CD244 contains two Ig-like (immunoglobulin-like) domains. CD244 is expressed in spleen, PBL, followed by lung, liver, testis and small intestine. CD244 interacts with CD48. Following phosphorylation, CD244 is able to recruit PTPN11/SHP-2 and SH2D1A/SAP. SLAMF4 modulate other receptor-ligand interactions to enhance leukocyte activation. CD244/2B4 is the only heterophilic receptor of SLAM family.
CAS Number
9000-83-3
NCBI Gene ID
51744
Swiss Prot
Q9BZW8
Accession Number
NP_057466
Tag
C-Fc Tag
Type
Recombinant Proteins
Source
HEK293 cells
Field of Research
Immunology, Stem Cell
Purity
>95% as determined by SDS-PAGE.
Buffer
50 mM tris, 100 mM glycine, pH7.5
Shipping Conditions
Room Temp
Storage Conditions
Lyophilized Protein should be stored at -20˚ C or lower for long term storage. Upon reconstitution, working aliquots should be stored at -20˚ C or -70˚ C. Avoid repeated freeze-thaw cycles.
Product Datasheet
https://www.prosci-inc.com/?datasheet_sku=96-002
Calculated Molecular Weight
48.9 kDa
Applications Notes
This recombinant protein can be used for WB. For research use only.
NCBI Official Name
CD244 molecule, natural killer cell receptor 2B4
NCBI Organism
Homo sapiens
Background Reference 01
Nakajima H., et al., 1999, Eur. J. Immunol. 29:1676-1683.
Background Reference 02
Kubin M.Z., et al., 1999, Eur. J. Immunol. 29:3466-3477.
Background Reference 03
Boles K.S., et al., 1999, Tissue Antigens 54:27-34.
Other Product Names
CD244, 2B4, SLAMF4, NKR2B4, NAIL, h2B4
Tested Applications
WB
Species
Human
Physical Properties
Lyophilized
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