NKp46 / NCR1 / CD335 Recombinant Protein
Product Specifications
Background
Natural cytotoxicity triggering receptor 1 (NCR1) is also known as Natural killer cell p46-related protein (NK-p46), Lymphocyte antigen 94 homolog (LY94), CD antigen CD335, which belongs to the natural cytotoxicity receptor (NCR) family. NCR1 contains two Ig-like (immunoglobulin-like) domains. NCR1 interacts with CD247 and FCER1G. NCR1 / CD335 may contribute to the increased efficiency of activated natural killer (NK) cells to mediate tumor cell lysis.
CAS Number
9000-83-3
NCBI Gene ID
9437
Swiss Prot
O76036
Accession Number
AAH64806.1
Tag
His Tag
Type
Recombinant Proteins
Source
HEK293 cells
Purity
>90% as determined by reduced SDS-PAGE.
Buffer
PBS, pH7.4
Shipping Conditions
Room Temp
Storage Conditions
Lyophilized Protein should be stored at -20˚ C or lower for long term storage. Upon reconstitution, working aliquots should be stored at -20˚ C or -70˚ C. Avoid repeated freeze-thaw cycles.
Calculated Molecular Weight
28.3 kDa
Applications Notes
This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 28.3 kDa. The protein migrates as 36-43 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
NCBI Official Name
Naturalcytotoxicitytriggeringreceptor1
NCBI Organism
Homo sapiens
Background Reference 01
Pessino A., et al., 1998, J. Exp. Med. 188:953-960.
Other Product Names
NCR1, LY94, CD335, NK-p46, hNKp46
Tested Applications
WB
Species
Human
Physical Properties
Lyophilized
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