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Myelin Oligodendrocyte Glycoprotein Recombinant Protein

Product Specifications

Background

Myelin Oligodendrocyte Glycoprotein (MOG) is a transmembrane protein, which is expressed exclusively in the CNS. MOG contains a single Ig-domain exposed to the extracellular space that allows autoantibodies easy access. MOG protein has been identified as a crucial autoantigen for multiple sclerosis in humans. MOG is capable to produce a demyelinating multiple sclerosis-like diseases in experimental animals, namely experimental autoimmune encephalomyelitis (EAE), in rodents and monkeys.

CAS Number

9000-83-3

NCBI Gene ID

4340

Swiss Prot

Q16653

Accession Number

Q16653

Tag

C-6 His tag

Type

Recombinant Proteins

Source

E. coli

Field of Research

Cancer, Neuroscience

Buffer

Lyophilized from a 0.2 um filtered solution of 20mM HAc-NaAc, 150mM NaCl, pH 4.5. It is not recommended to reconstitute to a concentration less than 100 ug/ml. Dissolve the lyophilized protein in ddH2O.

Shipping Conditions

Room Temp

Calculated Molecular Weight

15.2 kD

Applications Notes

This recombinant protein can be used for biological assays. For research use only.

NCBI Official Name

Myelin oligodendrocyte glycoprotein

NCBI Organism

Homo sapiens

Other Product Names

Myelin-Oligodendrocyte Glycoprotein, MOG

Species

Human

Protein ID

767928039

Physical Properties

Lyophilized

Frequently Asked Questions

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