Myelin Oligodendrocyte Glycoprotein Recombinant Protein
Product Specifications
Background
Myelin Oligodendrocyte Glycoprotein (MOG) is a transmembrane protein, which is expressed exclusively in the CNS. MOG contains a single Ig-domain exposed to the extracellular space that allows autoantibodies easy access. MOG protein has been identified as a crucial autoantigen for multiple sclerosis in humans. MOG is capable to produce a demyelinating multiple sclerosis-like diseases in experimental animals, namely experimental autoimmune encephalomyelitis (EAE), in rodents and monkeys.
CAS Number
9000-83-3
NCBI Gene ID
4340
Swiss Prot
Q16653
Accession Number
Q16653
Tag
C-6 His tag
Type
Recombinant Proteins
Source
E. coli
Field of Research
Cancer, Neuroscience
Buffer
Lyophilized from a 0.2 um filtered solution of 20mM HAc-NaAc, 150mM NaCl, pH 4.5. It is not recommended to reconstitute to a concentration less than 100 ug/ml. Dissolve the lyophilized protein in ddH2O.
Shipping Conditions
Room Temp
Calculated Molecular Weight
15.2 kD
Applications Notes
This recombinant protein can be used for biological assays. For research use only.
NCBI Official Name
Myelin oligodendrocyte glycoprotein
NCBI Organism
Homo sapiens
Other Product Names
Myelin-Oligodendrocyte Glycoprotein, MOG
Species
Human
Protein ID
767928039
Physical Properties
Lyophilized
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