MINPP1 Recombinant Protein
Product Specifications
Background
Multiple Inositol Polyphosphate Phosphatase 1/MINPP1 is an enzyme that removes 3-phosphate from inositol phosphate substrates. MINPP1 also converts 2,3 bisphosphoglycerate (2,3-BPG) to 2-phosphoglycerate. MINPP1 is synthesized as a 487 amino acid precursor that contains an 30 amino acid signal peptide and a 457 amino aicd mature chain. MINPP1 is widely expressed with the highest levels found in kidney, liver and placenta. It acts as a phosphoinositide 5- and phosphoinositide 6-phosphatase and regulates cellular levels of inositol pentakisphosphate (InsP5) and inositol hexakisphosphate (InsP6) . MINPP1 may play a role in bone development (endochondral ossification) .
NCBI Gene ID
9562
Swiss Prot
Q9UNW1
Accession Number
Q9UNW1
Tag
C-6 His tag
Type
Recombinant Proteins
Source
Human Cells
Field of Research
Signal Transduction
Buffer
Supplied as a 0.2 um filtered solution of 20mM TrisHCl, 150mM NaCl, 10% Glycerol, pH 7.5. It is not recommended to reconstitute to a concentration less than 100 ug/ml.
Shipping Conditions
Dry Ice
Product Datasheet
https://www.prosci-inc.com/?datasheet_sku=91-475
Calculated Molecular Weight
53.14 kD
Applications Notes
This recombinant protein can be used for biological assays. For research use only.
NCBI Official Name
Multiple inositol-polyphosphate phosphatase 1
NCBI Organism
Homo sapiens
Other Product Names
Multiple Inositol Polyphosphate Phosphatase 1, 2, 3-Bisphosphoglycerate 3-Phosphatase, 3-BPG Phosphatase, Inositol (1, 3, 4, 5) -Tetrakisphosphate 3-Phosphatase, Ins (1, 5) P (4) 3-Phosphatase, MINPP1, MIPP
Species
Human
Physical Properties
Liquid
CAS Number
9000-83-3
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