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Carbonic anhydrase 14 Recombinant Protein

Product Specifications

Background

Mouse Ca14, also known as Carbonic anhydrase 14, is a member of large family of zinc metalloenzymes .It could catalyze reversible hydration of carbon dioxide. The reaction is fundamental to many processes such as respiration, renal tubular acidification and bone resorption. Fifteen CA isoforms have been reported so far. They have different patterns of tissue-specific expression and physiologic roles. Some CAs may serve as markers for tumors and hypoxia. CA XIV is a polypeptide consisting of an extracellular N-terminal catalytic domain, a membrane-spanning segment and a short intracellular C- terminal segment with several potential phosphorylation sites. A subset of CAs lack CA activity due to point mutations but retain esterase function. CA14 is widely expressed in the central nervous system

NCBI Gene ID

23831

Swiss Prot

Q9WVT6

Accession Number

Q9WVT6

Tag

C-6 His tag

Type

Recombinant Proteins

Source

Human Cells

Field of Research

Cell Cycle, Obesity, Neuroscience, Signal Transduction, Cancer

Buffer

Supplied as a 0.2 um filtered solution of 20mM Tris,150mM NaCl, pH8.0. It is not recommended to reconstitute to a concentration less than 100 ug/ml.

Shipping Conditions

Dry Ice

Product Datasheet

https://www.prosci-inc.com/?datasheet_sku=92-482

Calculated Molecular Weight

31.8 kD

Applications Notes

This recombinant protein can be used for biological assays. For research use only.

NCBI Official Name

Carbonic anhydrase 14

NCBI Organism

Mus musculus

Other Product Names

Carbonic Anhydrase 14, Carbonate Dehydratase XIV, Carbonic Anhydrase XIV, CA-XIV, CA14

Species

Mouse

Physical Properties

Liquid

CAS Number

9000-83-3

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