Mitochondrial Fission 1 Protein Recombinant Protein
Product Specifications
Background
Mitochondrial Fission 1 Protein (FIS1) is a member of the FIS1 family. FIS1 is a single-pass membrane protein and contains one TPR repeat. FIS1 is part of the mitochondrial complex that promotes mitochondrial fission. FIS1 can induce cytochrome C discharge from the mitochondrion to the cytosol, eventually leading to apoptosis. In addition, FIS1 participates in peroxisomal growth and division. The C-terminus of FIS1 is required for mitochondrial or peroxisomal localization, while the N-terminus is necessary for mitochondrial or peroxisomal fission, localization and regulation of the interaction with DNM1L.
CAS Number
9000-83-3
NCBI Gene ID
51024
Swiss Prot
Q9Y3D6
Accession Number
Q9Y3D6
Tag
C-6 His tag
Type
Recombinant Proteins
Source
E. coli
Field of Research
Cancer, Other
Buffer
Lyophilized from a 0.2 um filtered solution of 20mM Tris, pH 8.0. It is not recommended to reconstitute to a concentration less than 100 ug/ml. Dissolve the lyophilized protein in ddH2O.
Shipping Conditions
Room Temp
Calculated Molecular Weight
15.2 kD
Applications Notes
This recombinant protein can be used for biological assays. For research use only.
NCBI Official Name
Fission, mitochondrial 1
NCBI Organism
Homo sapiens
Other Product Names
Mitochondrial Fission 1 Protein, FIS1 Homolog, hFis1, Tetratricopeptide Repeat Protein 11, TPR Repeat Protein 11, FIS1, TTC11, CGI-135
Species
Human
Physical Properties
Lyophilized
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