Mesothelin / MSLN (298-600) Recombinant Protein

Product Specifications

Background

Mesothelin (MSLN) is also known as CAK1 antigen, Pre-pro-megakaryocyte-potentiating factor, which belongs to the mesothelin family. Mesothelin / MSLN can be proteolytically cleaved into the following two chains by a furin-like convertase: Megakaryocyte-potentiating factor (MPF) and the cleaved form of mesothelin. Both MPF and the cleaved form of mesothelin are N-glycosylated. Mesothelin / MSLN can interacts with MUC16. The membrane-anchored forms of MSLN may play a role in cellular adhesion. MPF potentiates megakaryocyte colony formation in vitro.

CAS Number

9000-83-3

NCBI Gene ID

56047

Swiss Prot

Q61468

Accession Number

NP_061345.1

Tag

His Tag

Type

Recombinant Proteins

Source

HEK293 cells

Field of Research

Cancer

Purity

>90% as determined by SDS-PAGE.

Buffer

PBS, pH7.4

Shipping Conditions

Room Temp

Storage Conditions

Lyophilized Protein should be stored at -20˚ C or lower for long term storage. Upon reconstitution, working aliquots should be stored at -20˚ C or -70˚ C. Avoid repeated freeze-thaw cycles.

Calculated Molecular Weight

36.0 kDa

Applications Notes

This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 36.0 kDa. The protein migrates as 42-48 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.