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M-CSF Recombinant Protein (Animal Free)

Product Specifications

Background

M-CSF is a potent hematopoietic factor produced by a variety of cells, including lymphocytes, monocytes, fibroblasts, endothelial cells, myoblasts and osteoblasts. It is a key regulator of cellular proliferation, differentiation, and survival for blood monocytes, tissue macrophages, and their respective progenitor cells. M-CSF has been shown to play important roles in modulating dermal thickness and fertility. M-CSF is clinically used in the treatment of infection, malignancies and atherosclerosis. It facilitates hematopoietic recovery after bone marrow transplantation. Human M-CSF is reactive in murine systems, but the murine molecule exhibits no activity on human cells. Recombinant Rat M-CSF is a 36.2 kDa homodimeric protein consisting of two 155 amino acid polypeptide subunits.

CAS Number

9000-83-3

NCBI Gene ID

78965

Swiss Prot

Q8JZQ0

Type

Recombinant Proteins

Source

E. coli

Field of Research

Immunology, Stem Cell, Cancer

Purity

≥ 98% by SDS-PAGE gel and HPLC analyses.

Shipping Conditions

Room Temp

Storage Conditions

The recombinant protein is stable for at least 2 years from date of receipt at -20˚ C. Reconstituted protein is stable for at least 3 months when stored in working aliquots with a carrier protein at -20˚ C. As with any protein, exposing the recombinant protein to repeated freeze / thaw cycles is not recommended. When working with proteins care should be taken to keep recombinant protein at a cool and stable temperature.

NCBI Official Name

Colony stimulating factor 1 (macrophage)

NCBI Organism

Rattus norvegicus

Other Product Names

Macrophage Colony Stimulating Factor, CSF-1, MGI-IM

Species

Rat, Mouse

Physical Properties

Lyophilized

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