MMP-9 Recombinant Protein
Product Specifications
Background
Matrix metallopeptidase 9 (MMP-9) is an enzyme encoded by the MMP9 gene. This protein, which is produced by normal alveolar macrophages and granulocytes, can be activated by 4-aminophenylmercuric acetate and phorbol ester and up-regulated by ARHGEF4, SPATA13 and APC via the JNK signaling pathway in colorectal tumor cells. MMP-9 is involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, angiogenesis, bone development, wound healing, cell migration, learning and memory, as well as in pathological processes, such as arthritis, intracerebral hemorrhage, and metastasis.
CAS Number
9000-83-3
NCBI Gene ID
4318
Swiss Prot
P14780
Accession Number
P14780
Tag
C-6 His tag
Type
Recombinant Proteins
Source
Human Cells
Field of Research
Immunology, Signal Transduction, Other
Buffer
Supplied as a 0.2 um filtered solution of 20mM TrisHCl, 2mM CaCl2, 150mM NaCl, 0.05% Brij35 (w/v), pH 7.5. It is not recommended to reconstitute to a concentration less than 100 ug/ml.
Shipping Conditions
Dry Ice
Product Datasheet
https://www.prosci-inc.com/?datasheet_sku=92-376
Calculated Molecular Weight
77.4 kD
Applications Notes
This recombinant protein can be used for biological assays. For research use only.
NCBI Official Name
Matrix metallopeptidase 9
NCBI Organism
Homo sapiens
Other Product Names
Matrix metalloproteinase-9, 92 kDa gelatinase, 92 kDa type IV collagenase, Gelatinase B, MMP9
Species
Human
Protein ID
20149322
Physical Properties
Liquid
Curated Selection
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