MBL Recombinant Protein
Product Specifications
Background
Mannose-binding lectin (MBL) is also known as mannose-binding protein, mannan-binding protein (MBP), Mannose-binding protein C, Collectin-1 (COLEC1), MBL2, which belongs to the class of collectins in the C-type lectin superfamily. MBL contains one C-type lectin domain and one collagen-like domain. MBL has an oligomeric structure (400-700 kDa), built of subunits that contain three presumably identical peptide chains of about 30 kDa each. MBL is calcium-dependent lectin involved in innate immune defense. MBL binds mannose, fucose and N-acetylglucosamine on different microorganisms and activates the lectin complement pathway. MBL binds to late apoptotic cells. MBL may bind DNA.
NCBI Gene ID
4153
Swiss Prot
P11226
Accession Number
AAH96179
Tag
His Tag
Type
Recombinant Proteins
Source
HEK293 cells
Field of Research
Immunology
Buffer
PBS, pH7.4
Shipping Conditions
Room Temp
Storage Conditions
Lyophilized Protein should be stored at -20˚ C or lower for long term storage. Upon reconstitution, working aliquots should be stored at -20˚ C or -70˚ C. Avoid repeated freeze-thaw cycles.
Product Datasheet
https://www.prosci-inc.com/?datasheet_sku=96-922
Calculated Molecular Weight
24.8 kDa
Applications Notes
This recombinant protein can be used for WB. For research use only.
NCBI Official Name
Mannose-binding lectin (protein C) 2, soluble (opsonic defect)
NCBI Organism
Homo sapiens
Background Reference 01
Nauta A.J., et al., 2003, Eur. J. Immunol. 33:2853-2863.
Background Reference 02
Hirano M., et al., 2005, J. Immunol. 175:3177-3185.
Other Product Names
MBL, MBL2, MBP1, MBP-C, Collectin-1, COLEC1, HSMBPC, MBL2D, MBPD
Tested Applications
WB
Species
Human
Physical Properties
Lyophilized
CAS Number
9000-83-3
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