LAMP1 Recombinant Protein
Product Specifications
Background
Lysosome-Associated Membrane Glycoprotein 1 (LAMP1) is a single-pass type I membrane protein belonging to the LAMP family. LAMP1 is expressed largely in the endosome-lysosome membranes of cells.It shuttles between lysosomes, endosomes, and the plasma membrane. LAMP1 functions to present carbohydrate ligands to selectins and it has also been implicated in tumor cell metastasis. It has been proposed LAMP1 can be used as a therapeutic agent for certain cancers, as well as a marker for lysosomal storage disorders and degranulation on lymphocytes such as CD8+ and NK cells. Cell surface LAMP1 and LAMP2 have been shown to promote adhesion of human peripheral blood mononuclear cells (PBMC) to vascular endothelium, therefore they are possibly involved in the adhesion of PBMCs to the site of inflammation.
NCBI Gene ID
3916
Swiss Prot
P11279
Accession Number
P11279
Tag
C-6 His tag
Type
Recombinant Proteins
Source
Human Cells
Field of Research
Apoptosis, Autophagy, Innate Immunity
Buffer
Lyophilized from a 0.2 um filtered solution of 20mM PB, 150mM NaCl, pH 7.2. It is not recommended to reconstitute to a concentration less than 100 ug/ml. Dissolve the lyophilized protein in ddH2O.
Shipping Conditions
Room Temp
Product Datasheet
https://www.prosci-inc.com/?datasheet_sku=91-436
Calculated Molecular Weight
39.42 kD
Applications Notes
This recombinant protein can be used for biological assays. For research use only.
NCBI Official Name
Lysosomal associated membrane protein 1
NCBI Organism
Homo sapiens
Other Product Names
Lysosome-Associated Membrane Glycoprotein 1, LAMP-1, Lysosome-Associated Membrane Protein 1, CD107 Antigen-Like Family Member A, CD107a, LAMP1
Species
Human
Physical Properties
Lyophilized
CAS Number
9000-83-3
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