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LYPD3 Recombinant Protein

Product Specifications

Background

Ly6/PLAUR domain-containing protein 3 (LYPD3) is also known as MIG-C4 , C4.4A, GPI-anchored metastasis-associated protein C4.4A homolog and Matrigel-induced gene C4 protein, which is a cell membrane protein containing two UPAR/Ly6 domains. LYPD3 is expressed in placenta, skin and urothelium. LYPD3 is found in the majority of primary and metastatic transitional cell carcinomas (TCCs) and as well in breast cancer tissues, but not in adjacent normal tissues. LYPD3 play a role in supporting cell migration and it is not only probably involved in urothelial cell-matrix interactions, but also in tumor progression.

CAS Number

9000-83-3

NCBI Gene ID

27076

Swiss Prot

O95274

Accession Number

AAH39167

Tag

His Tag

Type

Recombinant Proteins

Source

HEK293 cells

Field of Research

Cancer, Other

Purity

>95% as determined by SDS-PAGE.

Buffer

PBS, pH7.4

Shipping Conditions

Room Temp

Storage Conditions

Lyophilized Protein should be stored at -20˚ C or lower for long term storage. Upon reconstitution, working aliquots should be stored at -20˚ C or -70˚ C. Avoid repeated freeze-thaw cycles.

Calculated Molecular Weight

28.7 kDa

Applications Notes

This recombinant protein can be used for WB. For research use only.

NCBI Official Name

LY6/PLAUR domain containing 3

NCBI Organism

Homo sapiens

Background Reference 01

Hansen L.V., et al., 2004, Biochem. Eng. J. 380:845-857.

Background Reference 02

Fletcher G.C., et al., 2003, Br. J. Cancer 88:579-585.

Background Reference 03

Oshiro R., et al., 2012, Cancer Sci. 103:1155-1164.

Other Product Names

LYPD3, MIG-C4, C4.4A

Tested Applications

WB

Species

Human

Physical Properties

Lyophilized

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