LYPD3 Recombinant Protein
Product Specifications
Background
Ly6/PLAUR domain-containing protein 3 (LYPD3) is also known as MIG-C4 , C4.4A, GPI-anchored metastasis-associated protein C4.4A homolog and Matrigel-induced gene C4 protein, which is a cell membrane protein containing two UPAR/Ly6 domains. LYPD3 is expressed in placenta, skin and urothelium. LYPD3 is found in the majority of primary and metastatic transitional cell carcinomas (TCCs) and as well in breast cancer tissues, but not in adjacent normal tissues. LYPD3 play a role in supporting cell migration and it is not only probably involved in urothelial cell-matrix interactions, but also in tumor progression.
CAS Number
9000-83-3
NCBI Gene ID
27076
Swiss Prot
O95274
Accession Number
AAH39167
Tag
His Tag
Type
Recombinant Proteins
Source
HEK293 cells
Field of Research
Cancer, Other
Purity
>95% as determined by SDS-PAGE.
Buffer
PBS, pH7.4
Shipping Conditions
Room Temp
Storage Conditions
Lyophilized Protein should be stored at -20˚ C or lower for long term storage. Upon reconstitution, working aliquots should be stored at -20˚ C or -70˚ C. Avoid repeated freeze-thaw cycles.
Calculated Molecular Weight
28.7 kDa
Applications Notes
This recombinant protein can be used for WB. For research use only.
NCBI Official Name
LY6/PLAUR domain containing 3
NCBI Organism
Homo sapiens
Background Reference 01
Hansen L.V., et al., 2004, Biochem. Eng. J. 380:845-857.
Background Reference 02
Fletcher G.C., et al., 2003, Br. J. Cancer 88:579-585.
Background Reference 03
Oshiro R., et al., 2012, Cancer Sci. 103:1155-1164.
Other Product Names
LYPD3, MIG-C4, C4.4A
Tested Applications
WB
Species
Human
Physical Properties
Lyophilized
Curated Selection
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