Fc gamma RIIIB Recombinant Protein

Product Specifications

Background

Low affinity immunoglobulin gamma Fc region receptor III-B, also known as Fc-gamma RIII-beta, FcR-10, IgG Fc receptor III-1, FCG3, FCGR3, CD16b and FCGR3B. FCGR3B is a GPI-anchor membrane protein and contains two Ig-like C2 type domains. FCGR3B can be expressed in orphonuclear leukocytes and stimulated eosinophils. FCGR3B can interact with INPP5D/SHIP1. FCGR3B localizes in the FCGR gene cluster is a CN polymorphic gene involved in the recruitment of polymorphonuclear neutrophils to sites of inflammation and their activation. FCGR3B may serve as a trap for immune complexes in the peripheral circulation which does not activate neutrophils.

CAS Number

9000-83-3

NCBI Gene ID

2215

Swiss Prot

O75015

Accession Number

O75015

Tag

C-Fc-6 His tag

Type

Recombinant Proteins

Source

Human Cells

Field of Research

Immunology

Buffer

Lyophilized from a 0.2 um filtered solution of PBS, pH7.4. It is not recommended to reconstitute to a concentration less than 100 ug/ml. Dissolve the lyophilized protein in ddH2O.

Shipping Conditions

Room Temp

Calculated Molecular Weight

51.4 kD

Applications Notes

This recombinant protein can be used for biological assays. For research use only.

NCBI Official Name

Fc fragment of IgG receptor IIIb

NCBI Organism

Homo sapiens

Other Product Names

Low affinity immunoglobulin gamma Fc region receptor III-B, Fc-gamma RIII-beta, FcR-10, IgG Fc receptor III-1, FCG3, FCGR3, CD16b and FCGR3B., CD16b, FCGR3B