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Lipopolysaccharide Recombinant Protein

Product Specifications

Background

Lipopolysaccharide-binding protein (LBP), a member of the BPI/LBP/Plunc superfamily, BPI/LBP family, is detected in blood serum. LBP plays a role in the innate immune response. Alao, LBP can bind to the lipid A moiety of bacterial lipopolysaccharides (LPS), a glycolipid present in the outer membrane of all Gram-negative bacteria, and act as an affinity enhancer for CD14, facilitating its association with LPS. Furthermore, LBP is able to promote the release of cytokines in response to bacterial lipopolysaccharide.

CAS Number

9000-83-3

NCBI Gene ID

3929

Swiss Prot

P18428

Accession Number

P18428

Tag

His Tag

Type

Recombinant Proteins

Source

HEK293 cells

Purity

>95% as determined by SDS-PAGE.

Buffer

PBS, pH 7.4

Shipping Conditions

Room Temp

Storage Conditions

Lyophilized Protein should be stored at -20˚ C or lower for long term storage. Upon reconstitution, working aliquots should be stored at -20˚ C or -70˚ C. Avoid repeated freeze-thaw cycles.

Calculated Molecular Weight

52.8 kDa

Applications Notes

This recombinant protein can be used for WB. For research use only.

NCBI Official Name

Lipopolysaccharide binding protein

NCBI Organism

Homo sapiens

Background Reference 01

Schumann R.R., et al., 1990, Science 249:1429-1431.

Background Reference 02

Hubacek J.A., et al., 1997, Biochem. Biophys. Res. Commun. 236:427-430.

Background Reference 03

Eckert J.K., et al., 2013, Immunity 39:647-660.

Other Product Names

Lambda Chain Binding Protein, Lambda Binding Protein, LBP

Tested Applications

WB

Species

Human

Physical Properties

Lyophilized

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