Lipopolysaccharide Recombinant Protein
Product Specifications
Background
Lipopolysaccharide-binding protein (LBP), a member of the BPI/LBP/Plunc superfamily, BPI/LBP family, is detected in blood serum. LBP plays a role in the innate immune response. Alao, LBP can bind to the lipid A moiety of bacterial lipopolysaccharides (LPS), a glycolipid present in the outer membrane of all Gram-negative bacteria, and act as an affinity enhancer for CD14, facilitating its association with LPS. Furthermore, LBP is able to promote the release of cytokines in response to bacterial lipopolysaccharide.
NCBI Gene ID
3929
Swiss Prot
P18428
Accession Number
P18428
Tag
His Tag
Type
Recombinant Proteins
Source
HEK293 cells
Purity
>95% as determined by SDS-PAGE.
Buffer
PBS, pH 7.4
Shipping Conditions
Room Temp
Storage Conditions
Lyophilized Protein should be stored at -20˚ C or lower for long term storage. Upon reconstitution, working aliquots should be stored at -20˚ C or -70˚ C. Avoid repeated freeze-thaw cycles.
Product Datasheet
https://www.prosci-inc.com/?datasheet_sku=96-506
Calculated Molecular Weight
52.8 kDa
Applications Notes
This recombinant protein can be used for WB. For research use only.
NCBI Official Name
Lipopolysaccharide binding protein
NCBI Organism
Homo sapiens
Background Reference 01
Schumann R.R., et al., 1990, Science 249:1429-1431.
Background Reference 02
Hubacek J.A., et al., 1997, Biochem. Biophys. Res. Commun. 236:427-430.
Background Reference 03
Eckert J.K., et al., 2013, Immunity 39:647-660.
Other Product Names
Lambda Chain Binding Protein, Lambda Binding Protein, LBP
Tested Applications
WB
Species
Human
Physical Properties
Lyophilized
CAS Number
9000-83-3
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