Limitin Recombinant Protein

Limitin, also called IFN-ζ, is a secreted interferon (IFN) -like glycoprotein. Limitin has approximately 30% sequence homology with IFN- alpha, IFN- beta , and IFN-ω and binds to the IFN- alpha/ beta receptors. Like IFN- alpha and IFN- beta , limitin has antiproliferative, immunomodulatory, and antiviral properties, it is unique in lacking influence on myeloid and erythroid progenitors. Similar dose requirement between limitin and IFN- alpha was observed for the enhancement of cytotoxic T lymphocyte activity, the augmentation of MHC class I expression, and the growth inhibition of a myelomonocytic leukemia cell line.

Lyophilized from a 0.2 um filtered solution of PBS, pH7.4. It is not recommended to reconstitute to a concentration less than 100 ug/ml. Dissolve the lyophilized protein in ddH2O.