LILRB3 Recombinant Protein
Product Specifications
Background
Leukocyte immunoglobulin-like receptor subfamily B member 3 is also known as LILRB3, ILT-5 or CD85a. LILRB3 plays an role as receptor for class I MHC antigens, which activated upon coligation of LILRB3 and immune receptors, such as FCGR2B and the B-cell receptor. LILRB3 and LILRA6 represent a pair of inhibitory/activating receptors with identical extracellular domains and unknown ligands. LILRB3 can mediate inhibitory signaling via immunoreceptor tyrosine-based inhibition motifs in its cytoplasmic tail whereas LILRA6 can signal through association with an activating adaptor molecule, FcRγ.
NCBI Gene ID
11025
Swiss Prot
AAB68668 (P288R)
Accession Number
AAB68668 (P288R)
Tag
Fc Tag
Type
Recombinant Proteins
Source
HEK293 cells
Field of Research
Immunology
Buffer
Tris with Glycine, Arginine and NaCl, pH7.5
Shipping Conditions
Room Temp
Storage Conditions
Lyophilized Protein should be stored at -20˚ C or lower for long term storage. Upon reconstitution, working aliquots should be stored at -20˚ C or -70˚ C. Avoid repeated freeze-thaw cycles.
Product Datasheet
https://www.prosci-inc.com/?datasheet_sku=96-916
Calculated Molecular Weight
72.8 kDa
Applications Notes
This recombinant protein can be used for WB. For research use only.
NCBI Official Name
LILRB3 protein
NCBI Organism
Homo sapiens
Background Reference 01
Bashirova AA., et al., 2014, Immunogenetics.66:1-8.
Background Reference 02
Huang J., et al., 2010, J Virol. 84 (18) :9463-9471. (3) Pfistershammer K., et al., 2009, Blood. 114 (11) :2323-2332.
Other Product Names
LILRB3, CD85a, ILT5
Tested Applications
WB
Species
Human
Physical Properties
Lyophilized
CAS Number
9000-83-3
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