CD84 Recombinant Protein
Product Specifications
Background
Leukocyte differentiation antigen CD84 is also known as SLAM family member 5 (SLAMF5), which belongs to immunoglobulin (Ig) superfamily. CD84 / SLAMF5 contains one Ig-like C2-type (immunoglobulin-like) domain. CD84 plays a role as adhesion receptor functioning by homophilic interactions and by clustering. CD84 / SLAMF5 increases proliferative responses of activated T-cells and SH2D1A/SAP does not seen be required for this process. Homophilic interactions enhance interferon gamma/IFNG secretion in lymphocytes and induce platelet stimulation via a SH2D1A/SAP-dependent pathway.
CAS Number
9000-83-3
NCBI Gene ID
8832
Swiss Prot
Q9UIB8
Accession Number
AAH20063
Tag
His Tag
Type
Recombinant Proteins
Source
HEK293 cells
Field of Research
Immunology, Signal Transduction
Purity
>95% as determined by SDS-PAGE.
Buffer
PBS, pH7.4
Shipping Conditions
Room Temp
Storage Conditions
Lyophilized Protein should be stored at -20˚ C or lower for long term storage. Upon reconstitution, working aliquots should be stored at -20˚ C or -70˚ C. Avoid repeated freeze-thaw cycles.
Calculated Molecular Weight
23.6 kDa
Applications Notes
This recombinant protein can be used for WB. For research use only.
NCBI Official Name
CD84 molecule
NCBI Organism
Homo sapiens
Background Reference 01
Martin M., et al., 2001, J. Immunol. 167:3668-3676.
Background Reference 02
Tangye S.G., et al., 2002, Eur. J. Immunol. 32:1640-1649.
Background Reference 03
Zaiss M., et al., 2003, Exp. Hematol. 31:798-805.
Other Product Names
CD84, SLAMF5, LY9B, SLAMF5, hCD84, mCD84
Tested Applications
WB
Species
Human
Physical Properties
Lyophilized
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