LIF Recombinant Protein
Product Specifications
Background
Leukemia Inhibitory Factor (LIF) is a lymphoid factor that promotes long-term maintenance of embryonic stem cells by suppressing spontaneous differentiation. LIF has a number of other activities including cholinergic neuron differentiation, control of stem cell pluripotency, bone and fat metabolism, mitogenesis of certain factor dependent cell lines and promotion of megakaryocyte production in vivo. Human and murine mature LIF exhibit a 78% sequence identity at the amino acid level. Human LIF is equally active on human and mouse cells. Murine LIF is approximately 1000 fold less active on human cells than human LIF.
NCBI Gene ID
3976
Swiss Prot
P15018
Accession Number
P15018
Tag
Tag Free
Type
Recombinant Proteins
Source
E. coli
Field of Research
Stem Cell
Buffer
Lyophilized from a 0.2 um filtered solution of 20mM PB, 150mM NaCl, 0.02% Tween 20, pH 7.4. It is not recommended to reconstitute to a concentration less than 100 ug/ml. Dissolve the lyophilized protein in ddH2O.
Shipping Conditions
Room Temp
Product Datasheet
https://www.prosci-inc.com/?datasheet_sku=91-014
Calculated Molecular Weight
19.7 kD
Applications Notes
This recombinant protein can be used for biological assays. For research use only.
NCBI Official Name
Leukemia inhibitory factor
NCBI Organism
Homo sapiens
Other Product Names
Leukemia Inhibitory Factor, LIF, Differentiation-Stimulating Factor, D Factor, Melanoma-Derived LPL Inhibitor, MLPLI, Emfilermin, HILDA
Species
Human
Protein ID
20149322
Physical Properties
Lyophilized
CAS Number
9000-83-3
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