KIR2DL4 Recombinant Protein

Product Specifications

Background

Killer cell immunoglobulin-like receptor 2DL4 (KIR2DL4) is a Single-pass type I membrane protein and contains 2 Ig-like C2-type (immunoglobulin-like) domains.It belongs to the immunoglobulin superfamily. KIR2DL4 is expressed in all NK cells and some T cells. KIR2DL4 activates the cytotoxicity of NK cells, despite the presence of an immunoreceptor tyrosine-based inhibition motif (ITIM) in its cytoplasmic tail. The ITIM was not necessary for activation of lysis by KIR2DL4. The activation signal of KIR2DL4 was sensitive to inhibition by another ITIM-containing receptor. The activation-deficient mutant of KIR2DL4 inhibited the signal delivered by the activating receptor CD16.

CAS Number

9000-83-3

NCBI Gene ID

3805

Swiss Prot

Q99706

Accession Number

Q99706

Tag

C-6 His tag

Type

Recombinant Proteins

Source

Human Cells

Field of Research

Immunology

Buffer

Lyophilized from a 0.2 um filtered solution of 20mM PB, 150mM NaCl, pH 7.4. It is not recommended to reconstitute to a concentration less than 100 ug/ml. Dissolve the lyophilized protein in ddH2O.

Shipping Conditions

Room Temp

Calculated Molecular Weight

25.34 kD

Applications Notes

This recombinant protein can be used for biological assays. For research use only.

NCBI Official Name

Killer cell immunoglobulin like receptor, two Ig domains and long cytoplasmic tail 4

NCBI Organism

Homo sapiens

Other Product Names

Killer Cell Immunoglobulin-Like Receptor 2DL4, CD158 Antigen-Like Family Member D, G9P, Killer Cell Inhibitory Receptor 103AS, KIR-103AS, MHC Class I NK Cell Receptor KIR103AS, CD158d, KIR2DL4, KIR103AS, KIR103