Ketohexokinase Recombinant Protein

Ketohexokinase, also known as Hepatic fructokinase, is a member of the carbohydrate kinase PfkB family. It exits as a homodimer and most abundant in liver, kidney, gut, spleen and pancreas. Low levels also found in adrenal, muscle, brain and eye.This enzyme catalyzes conversion of fructose to fructose-1-phosphate. It is the first enzyme with a specialized pathway that catabolizes dietary fructose. Defects in KHK are the cause of fructosuria.

Supplied as a 0.2 um filtered solution of 20mM TrisHCl,50nM KCl,10%Glycerol, pH7.4. It is not recommended to reconstitute to a concentration less than 100 ug/ml.