Kell Recombinant Protein
Product Specifications
Background
Kell blood group glycoprotein (KEL) is a single-pass type II membrane protein which belongs to the peptidase M13 family. It is expressed in Expressed at high levels in erythrocytes and testis, and, at lower levels, in skeletal muscle, tonsils, lymph node, spleen and appendix. KEL has been shown zinc endopeptidase with endothelin-3-converting enzyme activity. It cleaves EDN1, EDN2 and EDN3, with a marked preference for EDN3. It links via a single disulfide bond to the XK membrane protein that carries the Kx antigen.
CAS Number
9000-83-3
NCBI Gene ID
3792
Swiss Prot
P23276
Accession Number
P23276
Tag
C-6 His tag
Type
Recombinant Proteins
Source
Human Cells
Field of Research
Other
Buffer
Supplied as a 0.2 um filtered solution of 20mM PB,150mM NaCl, pH7.4. It is not recommended to reconstitute to a concentration less than 100 ug/ml.
Shipping Conditions
Dry Ice
Calculated Molecular Weight
78.4 kD
Applications Notes
This recombinant protein can be used for biological assays. For research use only.
NCBI Official Name
Kell blood group, metallo-endopeptidase
NCBI Organism
Homo sapiens
Other Product Names
Kell blood group glycoprotein, CD238, KEL
Species
Human
Protein ID
578877726
Physical Properties
Liquid
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