Jagged-2 Recombinant Protein
Product Specifications
Background
Jagged-2 is a putative Notch ligand involved in the mediation of Notch signaling, that can induce stromal cells to secrete IL-6, VEGF and IGF-1. Notch activation can interact with NF-kappaB and C-myc to promote the proliferation and to inhibit the apoptosis of MM cells, showing in the relationship between the incidence of myeloma and drug resistance. Jagged-2 is also involved in limb development.
CAS Number
9000-83-3
NCBI Gene ID
3714
Swiss Prot
Q61483
Accession Number
Q9Y219
Tag
Fc Tag
Type
Recombinant Proteins
Source
HEK293 cells
Field of Research
Cancer, Neuroscience, Obesity, Signal Transduction
Concentration
0.1mg/ml after reconstitution.
Buffer
Contains PBS + 0.02 % CHAPS. Reconstitute with 100 μ l sterile water.
Shipping Conditions
Room Temp
Storage Conditions
Stable for at least 6 months after receipt when stored at -20˚ C.
Applications Notes
This recombinant proteins is for research use only.
NCBI Official Name
Jagged 2
NCBI Organism
Homo sapiens
Other Product Names
Protein Jagged-2, hJ2, JAG2
Species
Human
Protein ID
21704277
Physical Properties
Lyophilized
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