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Jagged-2 Recombinant Protein

Product Specifications

Background

Jagged-2 is a putative Notch ligand involved in the mediation of Notch signaling, that can induce stromal cells to secrete IL-6, VEGF and IGF-1. Notch activation can interact with NF-kappaB and C-myc to promote the proliferation and to inhibit the apoptosis of MM cells, showing in the relationship between the incidence of myeloma and drug resistance. Jagged-2 is also involved in limb development.

NCBI Gene ID

3714

Swiss Prot

Q61483

Accession Number

Q9Y219

Tag

Fc Tag

Type

Recombinant Proteins

Source

HEK293 cells

Field of Research

Cancer, Neuroscience, Obesity, Signal Transduction

Concentration

0.1mg/ml after reconstitution.

Buffer

Contains PBS + 0.02 % CHAPS. Reconstitute with 100 μ l sterile water.

Shipping Conditions

Room Temp

Storage Conditions

Stable for at least 6 months after receipt when stored at -20˚ C.

Product Datasheet

https://www.prosci-inc.com/?datasheet_sku=90-167

Applications Notes

This recombinant proteins is for research use only.

NCBI Official Name

Jagged 2

NCBI Organism

Homo sapiens

Other Product Names

Protein Jagged-2, hJ2, JAG2

Species

Human

Protein ID

21704277

Physical Properties

Lyophilized

CAS Number

9000-83-3

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