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Jagged-2 Recombinant Protein

Product Specifications

Background

Jagged-2 is a putative Notch ligand involved in the mediation of Notch signaling, that can induce stromal cells to secrete IL-6, VEGF and IGF-1. Notch activation can interact with NF-kappaB and C-myc to promote the proliferation and to inhibit the apoptosis of MM cells, showing in the relationship between the incidence of myeloma and drug resistance. Jagged-2 is also involved in limb development.

CAS Number

9000-83-3

NCBI Gene ID

3714

Swiss Prot

Q61483

Accession Number

Q9Y219

Tag

Fc Tag

Type

Recombinant Proteins

Source

HEK293 cells

Field of Research

Cancer, Neuroscience, Obesity, Signal Transduction

Concentration

0.1mg/ml after reconstitution.

Buffer

Contains PBS + 0.02 % CHAPS. Reconstitute with 100 μ l sterile water.

Shipping Conditions

Room Temp

Storage Conditions

Stable for at least 6 months after receipt when stored at -20˚ C.

Applications Notes

This recombinant proteins is for research use only.

NCBI Official Name

Jagged 2

NCBI Organism

Homo sapiens

Other Product Names

Protein Jagged-2, hJ2, JAG2

Species

Human

Protein ID

21704277

Physical Properties

Lyophilized

Frequently Asked Questions

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