SARS-CoV-2 (COVID-19) S1 Recombinant Protein NTD
Product Specifications
Background
It's been reported that Coronavirus can infect the human respiratory epithelial cells through interaction with the human ACE2 receptor. The spike protein is a large type I transmembrane protein containing two subunits, S1 and S2. S1 mainly contains a receptor binding domain (RBD), which is responsible for recognizing the cell surface receptor. S2 contains basic elements needed for the membrane fusion.The S protein plays key parts in the induction of neutralizing-antibody and T-cell responses, as well as protective immunity.
NCBI Gene ID
43740568
Swiss Prot
P0DTC2
Accession Number
QHD43416.1
Tag
His Tag
Type
Recombinant Proteins
Source
HEK293 cells
Field of Research
Infectious Disease, COVID-19
Purity
>90% as determined by SDS-PAGE.
Buffer
PBS, pH7.3
Shipping Conditions
Room Temp
Storage Conditions
Lyophilized Protein should be stored at -20˚ C or lower for long term storage. Upon reconstitution, working aliquots should be stored at -20˚ C or -70˚ C. Avoid repeated freeze-thaw cycles.
Product Datasheet
https://www.prosci-inc.com/?datasheet_sku=11-198
Calculated Molecular Weight
34.9 kDa
Applications Notes
This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 34.9 kDa. The protein migrates as 45-65 kDa under reducing (R) condition (SDS-PAGE) due to Glycosylation.
NCBI Official Name
Surface glycoprotein
NCBI Organism
Homo sapiens
Background Reference 01
Wan Y, et al. J Virol. 2020. pii: JVI.00127-20.
Background Reference 02
Benvenuto D, et al. J Med Virol. 2020.
Background Reference 03
Chang CY, et al. AMB Express. 2020. 10 (1) :20.
Other Product Names
S1 protein NTD, Spike protein S1 NTD, BetaCoV S1-NTD, COVID-19
Tested Applications
ELISA, WB
Species
SARS-CoV-2
Physical Properties
Lyophilized
CAS Number
9000-83-3
Curated Selection
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