FNDC5:Fc Recombinant Protein
Product Specifications
Background
Irisin is a recently described exercise-induced hormone secreted by skeletal muscle in mice and humans. Irisin activates beige fat cells (beige cells have a gene expression pattern distinct from either white or brown fat and are preferentially sensitive to the polypeptide hormone Irisin) . Irisin is cleaved from the type I membrane protein FNDC5 and improves systemic metabolism by increasing energy expenditure. The membrane receptor FNDC5 can be cleaved by an unknown protease to release the Irisin protein (aa 32-143 for human) and potentially also the FNDC5 (extracellular domain, aa 32-153 for human) .
CAS Number
9000-83-3
NCBI Gene ID
252995
Swiss Prot
P13500
Accession Number
Q8NAU1
Tag
Fc Tag
Type
Recombinant Proteins
Source
HEK293 cells
Field of Research
Obesity
Concentration
0.1mg/ml after reconstitution.
Buffer
Contains PBS. Reconstitute with 100 μ l sterile water.
Shipping Conditions
Room Temp
Storage Conditions
Stable for at least 6 months after receipt when stored at -20˚ C.
Applications Notes
This recombinant proteins is for research use only.
NCBI Official Name
Fibronectin type III domain containing 5
NCBI Organism
Homo sapiens
Other Product Names
Fibronectin Type III Domain-containing Protein 5, Fibronectin Type III Repeat-containing Protein 2.
Species
Human, Mouse, Rat
Protein ID
403314395
Physical Properties
Lyophilized
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