FNDC4 Recombinant Protein
Product Specifications
Background
Irisin is a recently described exercise-induced hormone secreted by skeletal muscle in mice and humans. Irisin activates beige fat cells (beige cells have a gene expression pattern distinct from either white or brown fat and are preferentially sensitive to the polypeptide hormone irisin) . Irisin is cleaved from the type I membrane protein FNDC5 and improves systemic metabolism by increasing energy expenditure. FNDC4 is an ortholog of FNDC5 with 50% identity and 86% similarity compared to Irisin. FNDC4 as well as FNDC5 are extremely well conserved between species. The function of FNDC4 is unknown. The human FNDC4 gene is highly enriched in liver, brain tissue and adipocytes.
CAS Number
9000-83-3
NCBI Gene ID
64838
Swiss Prot
Q9NYJ7
Accession Number
Q9H6D8
Tag
Tag Free
Type
Recombinant Proteins
Source
E. coli
Field of Research
Cell Cycle
Concentration
0.1mg/ml after reconstitution.
Buffer
Contains PBS. Reconstitute with 100 μ l sterile water.
Shipping Conditions
Room Temp
Storage Conditions
Stable for at least 6 months after receipt when stored at -20˚ C.
Product Datasheet
https://www.prosci-inc.com/?datasheet_sku=90-304
Applications Notes
This recombinant proteins is for research use only.
NCBI Official Name
Fibronectin type III domain containing 4
NCBI Organism
Homo sapiens
Other Product Names
Fibronectin Type III Domain-containing Protein 4, Fibronectin Type III Repeat-containing Protein 1
Species
Dog, Human, Monkey, Mouse, Rat
Protein ID
74762739
Physical Properties
Lyophilized
Curated Selection
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