IL-4 Recombinant Protein
Product Specifications
Background
Interleukin-4 (IL-4) is a cytokine produced by type 2 helper T cells, the Th2 cells. These cells tends to make a specific set of lymphokines including IL-4, IL-5, IL-6, IL-10, IL-13, IL-3 and GM-CSF and fail to produce IL-2, IFN-gamma, and lymphotoxin (TNF-beta) . In addition, mast cells can produce IL-4. IL-4 exerts numerous effects on various hematopoietic cell types. On B cells, IL-4 promotes immunoglobulin class switching to IgE and IgG1 isotypes and upregulates MHC class II and CD23 expression. IL-4 promotes survival, growth and differentiation of both T and B lymphocytes, mast cells and endothelial cells. In addition, IL-4 inhibits the production of TNF, IL-1 and IL-6 by macrophages.
NCBI Gene ID
16189
Swiss Prot
Q14213
Accession Number
NP_067258
Tag
His Tag
Type
Recombinant Proteins
Source
E. coli
Field of Research
Innate Immunity
Buffer
Lyophilized from 0.2um-filtered solution in PBS (pH 7.4) . Reconstituted in sterile H2O not less than 100 μ g/ml, which can then be further diluted in other aqueous solutions.
Shipping Conditions
Room Temp
Storage Conditions
Stable for at least 1 year after receipt when stored at -20˚ C. Working aliquots are stable for up to 3 months when stored at -20˚ C.
Product Datasheet
https://www.prosci-inc.com/?datasheet_sku=90-481
Applications Notes
This recombinant proteins is for research use only.
NCBI Official Name
Interleukin 4
NCBI Organism
Mus musculus
Other Product Names
Interleukin-4, B Cell Stimulatory Factor 1, BSF-1
Species
Mouse
Protein ID
10946584
Physical Properties
Lyophilized
CAS Number
9000-83-3
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