WSX 1 Recombinant Protein
Product Specifications
Background
Interleukin-27 receptor subunit alpha (IL27RA) is also known as Cytokine receptor WSX-1, Cytokine receptor-like 1, Type I T-cell cytokine receptor (TCCR), ZcytoR1, IL27RA belongs to the type I cytokine receptor family and type 2 subfamily. IL27RA contains three fibronectin type-III domains. IL27RA is highly expressed in lymphoid tissues such as spleen, lymph nodes and peripheral blood leukocytes. IL27RA is receptor for IL27, but requires IL6ST/gp130 to mediate signal transduction in response to IL27. IL27RA involved in the regulation of Th1-type immune responses. IL27RA also appears to be involved in innate defense mechanisms.
CAS Number
9000-83-3
NCBI Gene ID
9466
Swiss Prot
Q6UWB1
Accession Number
AAH28003
Tag
C-Fc Tag
Type
Recombinant Proteins
Source
HEK293 cells
Field of Research
Apoptosis
Purity
>95% as determined by SDS-PAGE.
Buffer
50 mM tris, 100 mM glycine, pH7.5
Shipping Conditions
Room Temp
Storage Conditions
Lyophilized Protein should be stored at -20˚ C or lower for long term storage. Upon reconstitution, working aliquots should be stored at -20˚ C or -70˚ C. Avoid repeated freeze-thaw cycles.
Calculated Molecular Weight
79 kDa
Applications Notes
This recombinant protein can be used for WB. For research use only.
NCBI Official Name
Interleukin 27 receptor, alpha
NCBI Organism
Homo sapiens
Background Reference 01
Sprecher C.A., et al., 1998, Biochem. Biophys. Res. Commun. 246:82-90.
Background Reference 02
Chen Q., et al., 2000, Nature 407:916-920.
Background Reference 03
Pflanz S., et al., 2004, J. Immunol. 172:2225-2231.
Other Product Names
IL27RA, CRL1, TCCR, WSX1
Tested Applications
WB
Species
Human
Physical Properties
Lyophilized
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