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WSX 1 Recombinant Protein

Product Specifications

Background

Interleukin-27 receptor subunit alpha (IL27RA) is also known as Cytokine receptor WSX-1, Cytokine receptor-like 1, Type I T-cell cytokine receptor (TCCR), ZcytoR1, IL27RA belongs to the type I cytokine receptor family and type 2 subfamily. IL27RA contains three fibronectin type-III domains. IL27RA is highly expressed in lymphoid tissues such as spleen, lymph nodes and peripheral blood leukocytes. IL27RA is receptor for IL27, but requires IL6ST/gp130 to mediate signal transduction in response to IL27. IL27RA involved in the regulation of Th1-type immune responses. IL27RA also appears to be involved in innate defense mechanisms.

NCBI Gene ID

9466

Swiss Prot

Q6UWB1

Accession Number

AAH28003

Tag

C-Fc Tag

Type

Recombinant Proteins

Source

HEK293 cells

Field of Research

Apoptosis

Purity

>95% as determined by SDS-PAGE.

Buffer

50 mM tris, 100 mM glycine, pH7.5

Shipping Conditions

Room Temp

Storage Conditions

Lyophilized Protein should be stored at -20˚ C or lower for long term storage. Upon reconstitution, working aliquots should be stored at -20˚ C or -70˚ C. Avoid repeated freeze-thaw cycles.

Product Datasheet

https://www.prosci-inc.com/?datasheet_sku=96-455

Calculated Molecular Weight

79 kDa

Applications Notes

This recombinant protein can be used for WB. For research use only.

NCBI Official Name

Interleukin 27 receptor, alpha

NCBI Organism

Homo sapiens

Background Reference 01

Sprecher C.A., et al., 1998, Biochem. Biophys. Res. Commun. 246:82-90.

Background Reference 02

Chen Q., et al., 2000, Nature 407:916-920.

Background Reference 03

Pflanz S., et al., 2004, J. Immunol. 172:2225-2231.

Other Product Names

IL27RA, CRL1, TCCR, WSX1

Tested Applications

WB

Species

Human

Physical Properties

Lyophilized

CAS Number

9000-83-3

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