IL-18 binding protein Recombinant Protein
Product Specifications
Background
Interleukin-18-binding protein, also known as Tadekinig-alfa and IL18BP, contains 1 Ig-like C2-type domain. IL18BP is constitutively expressed and secreted in mononuclear cells. IL18BP functions as an IL18 inhibitor. IL18BP binds to IL18, prevents the binding of IL18 to its receptor, and thus inhibits IL18-induced IFN-gamma production. It has been shown that IL18BP may be a promising molecular approach to inhibit neointimal hyperplasia and arteriosclerosis progression following coronary and peripheral angioplasty.
NCBI Gene ID
10068
Swiss Prot
O95998
Accession Number
O95998
Tag
C-Fc tag
Type
Recombinant Proteins
Source
Human Cells
Field of Research
Chemokines & Cytokines
Buffer
Lyophilized from a 0.2 um filtered solution of 20mM PB,150mM NaCl, pH7.2. It is not recommended to reconstitute to a concentration less than 100 ug/ml. Dissolve the lyophilized protein in ddH2O.
Shipping Conditions
Room Temp
Product Datasheet
https://www.prosci-inc.com/?datasheet_sku=91-814
Calculated Molecular Weight
44.7 kD
Applications Notes
This recombinant protein can be used for biological assays. For research use only.
NCBI Official Name
Interleukin 18 binding protein
NCBI Organism
Homo sapiens
Other Product Names
Interleukin-18-binding protein, Tadekinig-alfa and IL18BP, IL-18BP
Species
Human
Protein ID
530384410
Physical Properties
Lyophilized
CAS Number
9000-83-3
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