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IL18 R1 Recombinant Protein

Product Specifications

Background

Interleukin-18 receptor 1 (IL18R1) is also known as CD218 antigen-like family member A (CD218a), IL1 receptor-related protein (IL-1Rrp or IL1R-rp), CDw218a, IL18Ra, IL1RRP, which belongs to the interleukin-1 receptor family. IL18R1 contains three Ig-like C2-type (immunoglobulin-like) domains and one TIR domain. IL18R1 is receptor for interleukin 18 (IL-18) . IL18R1 binds to the agonist leads to the activation of NF-kappa-B, but does not bind IL1A/interleukin-1 alpha or IL1B/interleukin-1 beta.

CAS Number

9000-83-3

NCBI Gene ID

8809

Swiss Prot

Q13478

Accession Number

AAH69575

Tag

C-Fc Tag

Type

Recombinant Proteins

Source

HEK293 cells

Purity

>95% as determined by SDS-PAGE.

Buffer

Tris with Glycine, Arginine and NaCl, pH7.5

Shipping Conditions

Room Temp

Storage Conditions

Lyophilized Protein should be stored at -20˚ C or lower for long term storage. Upon reconstitution, working aliquots should be stored at -20˚ C or -70˚ C. Avoid repeated freeze-thaw cycles.

Calculated Molecular Weight

62.4 kDa

Applications Notes

This recombinant protein can be used for WB. For research use only.

NCBI Official Name

Interleukin 18 receptor 1

NCBI Organism

Homo sapiens

Background Reference 01

Parnet P., et al., 1996, J. Biol. Chem. 271:3967-3970.

Background Reference 02

Torigoe K., et al., 1997, J. Biol. Chem. 272:25737-25742.

Other Product Names

IL18R1, IL1RRP, CD218a, IL18Ra

Tested Applications

WB

Species

Human

Physical Properties

Lyophilized

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