IL1R3 Recombinant Protein
Product Specifications
Background
Interleukin-1 receptor accessory protein (IL1RAP or IL-1RAcP) is also known as Interleukin-1 receptor 3 (IL-1R-3 or IL-1R3), C3orf13, which belongs to the interleukin-1 receptor family. IL1RAP contains three Ig-like C2-type (immunoglobulin-like) domains and one TIR domain. IL1RAP is detected in liver, skin, placenta, thymus and lung. IL-1R3 / IL1RAP is coreceptor with IL1R1, associates with IL1R1 bound to IL1B to form the high affinity interleukin-1 receptor complex which mediates interleukin-1-dependent activation of NF-kappa-B and other pathways.
CAS Number
9000-83-3
NCBI Gene ID
3556
Swiss Prot
Q9NPH3
Accession Number
Q9NPH3
Tag
C-Fc Tag
Type
Recombinant Proteins
Source
HEK293 cells
Field of Research
Chemokines & Cytokines
Purity
>95% as determined by SDS-PAGE.
Buffer
50 mM tris, 100 mM glycine, pH7.5
Shipping Conditions
Room Temp
Storage Conditions
Lyophilized Protein should be stored at -20˚ C or lower for long term storage. Upon reconstitution, working aliquots should be stored at -20˚ C or -70˚ C. Avoid repeated freeze-thaw cycles.
Calculated Molecular Weight
65.7 kDa
Applications Notes
This recombinant protein can be used for WB. For research use only.
NCBI Official Name
Interleukin 1 receptor accessory protein
NCBI Organism
Homo sapiens
Background Reference 01
Huang J., et al., 1997, Proc. Natl. Acad. Sci. U.S.A. 94:12829-12832.
Background Reference 02
Jensen L.E., et al., 2000, J. Immunol. 164:5277-5286.
Background Reference 03
Smith D.E., et al., 2003, Immunity 18:87-96.
Other Product Names
IL1RAP, IL-1RAcP, C3orf13, IL1R3
Tested Applications
WB
Species
Human
Physical Properties
Lyophilized
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