IL-6R Recombinant Protein
Product Specifications
Background
Interleukin 6 receptor (IL-6R; CD126) is a type I cytokine receptor, which is a protein complex consisting of an IL-6 receptor subunit (IL-6R) and interleukin 6 signal transducer glycoprotein 130 (gp130) . It is a potent pleiotropic cytokine that regulates cell growth and differentiation and plays an important role in immune response. Dysregulated production of IL-6 and IL-6R are implicated in the pathogenesis of many diseases, such as multiple myeloma, autoimmune diseases and prostate cancer.
CAS Number
9000-83-3
NCBI Gene ID
16194
Swiss Prot
P36941
Accession Number
CAA37810
Tag
Fc Tag
Type
Recombinant Proteins
Source
CHO cells
Field of Research
Signal Transduction
Buffer
Lyophilized from 0.2um-filtered solution in PBS. Reconstitute at 100 μ g/ml in sterile PBS.
Shipping Conditions
Room Temp
Storage Conditions
Stable for at least 1 year after receipt when stored at -20˚ C. Working aliquots are stable for up to 3 months when stored at -20˚ C.
Applications Notes
This recombinant proteins is for research use only.
NCBI Official Name
Interleukin 6 receptor, alpha
NCBI Organism
Mus musculus
Other Product Names
Interleukin-6 Receptor Subunit alpha, IL6RA, CD126
Species
Mouse
Protein ID
52693
Physical Properties
Lyophilized
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