IL-6 Recombinant Protein

Product Specifications

Background

Interleukin 6 (IL-6) is a pleiotropic alpha-helical cytokine that plays important roles in acute phase reactions, inflammation, hematopoiesis, bone metabolism and cancer progression. IL-6 activity is essential for the transition from acute inflammation to either acquired immunity or chronic inflammatory disease. It is secreted by multiple cell types as a 22kDa-28kDa phosphorylated and variably glycosylated molecule. IL-6 induces signaling through a cell surface heterodimeric receptor complex composed of a ligand binding subunit (IL-6R) and a signal transducing subunit (gp130) . IL-6 is a key factor for the growth of plasma cells.

CAS Number

9000-83-3

NCBI Gene ID

3569

Swiss Prot

O35228

Accession Number

NP_000591

Tag

Fc Tag

Type

Recombinant Proteins

Source

CHO cells

Field of Research

Cancer, Chemokines & Cytokines, Immunology, Neuroscience, Obesity, Signal Transduction

Buffer

Lyophilized from 0.2um-filtered solution in PBS. Reconstitute in 50 μ l sterile water. Add 1X PBS to the desired protein concentration.

Shipping Conditions

Room Temp

Storage Conditions

Stable for at least 1 year after receipt when stored at -20˚ C. Working aliquots are stable for up to 3 months when stored at -20˚ C.

Applications Notes

This recombinant proteins is for research use only.

NCBI Official Name

Interleukin 6

NCBI Organism

Homo sapiens

Other Product Names

Interleukin-6, B Cell Stimulatory Factor 2, BSF-2, CTL Differentiation Factor, CDF, Interferon beta2, IFN-beta2

Species

Human

Protein ID

10834984

Physical Properties

Lyophilized

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