IL-6 Recombinant Protein
Product Specifications
Background
Interleukin 6 (IL-6) is a pleiotropic alpha-helical cytokine that plays important roles in acute phase reactions, inflammation, hematopoiesis, bone metabolism and cancer progression. IL-6 activity is essential for the transition from acute inflammation to either acquired immunity or chronic inflammatory disease. It is secreted by multiple cell types as a 22kDa-28kDa phosphorylated and variably glycosylated molecule. IL-6 induces signaling through a cell surface heterodimeric receptor complex composed of a ligand binding subunit (IL-6R) and a signal transducing subunit (gp130) . IL-6 is a key factor for the growth of plasma cells.
CAS Number
9000-83-3
NCBI Gene ID
3569
Swiss Prot
O35228
Accession Number
NP_000591
Tag
Fc Tag
Type
Recombinant Proteins
Source
CHO cells
Field of Research
Cancer, Chemokines & Cytokines, Immunology, Neuroscience, Obesity, Signal Transduction
Buffer
Lyophilized from 0.2um-filtered solution in PBS. Reconstitute in 50 μ l sterile water. Add 1X PBS to the desired protein concentration.
Shipping Conditions
Room Temp
Storage Conditions
Stable for at least 1 year after receipt when stored at -20˚ C. Working aliquots are stable for up to 3 months when stored at -20˚ C.
Applications Notes
This recombinant proteins is for research use only.
NCBI Official Name
Interleukin 6
NCBI Organism
Homo sapiens
Other Product Names
Interleukin-6, B Cell Stimulatory Factor 2, BSF-2, CTL Differentiation Factor, CDF, Interferon beta2, IFN-beta2
Species
Human
Protein ID
10834984
Physical Properties
Lyophilized
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