IL13RA1 Recombinant Protein
Product Specifications
Background
Interleukin 13 receptor, alpha 1 is also known as IL13RA1, NR4 and CD213A1 (cluster of differentiation 213A1), The IL13 Rα1 cDNA encodes a 427 amino acid (aa) residue precursor protein with a putative 21 aa residue signal peptide, a 324 aa residue extracellular domain, a 23 aa residue transmembrane region and a 59 aa residue cytoplasmic tail. Human and mouseIL13Rα1 share 76% aa sequence identity. IL13RA1 is a subunit of the interleukin 13 receptor. This subunit forms a receptor complex with IL4 receptor alpha, a subunit shared by IL13 and IL4 receptors. This subunit serves as a primary IL13-binding subunit of the IL13 receptor, and may also be a component of IL4 receptors. This protein has been shown to bind tyrosine kinase TYK2, and thus may mediate the signaling processes that lead to the activation of JAK1, STAT3 and STAT6 induced by IL13 and IL4.
CAS Number
9000-83-3
NCBI Gene ID
16164
Swiss Prot
O09030
Accession Number
NP_598751
Tag
C-Fc Tag
Type
Recombinant Proteins
Source
HEK293 cells
Purity
>95% as determined by SDS-PAGE.
Buffer
Tris with Glycine, Arginine and NaCl, pH7.5
Shipping Conditions
Room Temp
Storage Conditions
Lyophilized Protein should be stored at -20˚ C or lower for long term storage. Upon reconstitution, working aliquots should be stored at -20˚ C or -70˚ C. Avoid repeated freeze-thaw cycles.
Calculated Molecular Weight
62.7 kDa
Applications Notes
This recombinant protein can be used for WB. For research use only.
NCBI Official Name
Interleukin 13 receptor, alpha 1
NCBI Organism
Mus musculus
Background Reference 01
Caput, D. et al., 1996, J. Biol. Chem. 271:16921.
Background Reference 02
Donaldson, D.D. et al., 1998, J. Immunol. 161:2317.
Background Reference 03
Hilton, D.J. et al., 1996, Proc. Natl. Acad. Sci. USA 93:497.
Other Product Names
IL13RA1, CD213A1, IL-13Ra, NR4, RP13-128O4.2, IL13Rα1
Tested Applications
WB
Species
Mouse
Physical Properties
Lyophilized
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
