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ST2 Recombinant Protein

Product Specifications

Background

Interleukin 1 receptor-like 1 (IL1RL1) is also known as ST2, DER4, FIT-1, IL33R, ST2L, ST2V, which belongs to the interleukin-1 receptor family. IL1RL1 contains three Ig-like C2-type (immunoglobulin-like) domains and one TIR domain. IL1RL1 is receptor for interleukin-33 (IL-33), its stimulation recruits MYD88, IRAK1, IRAK4, and TRAF6, followed by phosphorylation of MAPK3/ERK1 and/or MAPK1/ERK2, MAPK14, and MAPK8. IL1RL1 possibly involved in helper T-cell function. IL1RL1 can interact with MYD88, IRAK1, IRAK4, and TRAF6.

CAS Number

9000-83-3

NCBI Gene ID

9173

Swiss Prot

Q01638

Accession Number

NP_003847

Tag

C-Fc Tag

Type

Recombinant Proteins

Source

HEK293 cells

Field of Research

Innate Immunity

Buffer

Tris with Glycine, Arginine and NaCl, pH7.5

Shipping Conditions

Room Temp

Storage Conditions

Lyophilized Protein should be stored at -20˚ C or lower for long term storage. Upon reconstitution, working aliquots should be stored at -20˚ C or -70˚ C. Avoid repeated freeze-thaw cycles.

Calculated Molecular Weight

61.0 kDa

Applications Notes

This recombinant protein can be used for WB. For research use only.

NCBI Official Name

Interleukin 1 receptor-like 1

NCBI Organism

Homo sapiens

Background Reference 01

Tago K., et al., 2001, Biochem. Biophys. Res. Commun. 285:1377-1383.

Background Reference 02

Schmitz J., et al., 2005, Immunity 23:479-490.

Other Product Names

IL1RL1, DER4, FIT-1, IL33R, ST2, ST2L, ST2V, T1

Tested Applications

WB

Species

Human

Physical Properties

Lyophilized

Frequently Asked Questions

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