ST2 Recombinant Protein
Product Specifications
Background
Interleukin 1 receptor-like 1 (IL1RL1) is also known as ST2, DER4, FIT-1, IL33R, ST2L, ST2V, which belongs to the interleukin-1 receptor family. IL1RL1 contains three Ig-like C2-type (immunoglobulin-like) domains and one TIR domain. IL1RL1 is receptor for interleukin-33 (IL-33), its stimulation recruits MYD88, IRAK1, IRAK4, and TRAF6, followed by phosphorylation of MAPK3/ERK1 and/or MAPK1/ERK2, MAPK14, and MAPK8. IL1RL1 possibly involved in helper T-cell function. IL1RL1 can interact with MYD88, IRAK1, IRAK4, and TRAF6.
CAS Number
9000-83-3
NCBI Gene ID
9173
Swiss Prot
Q01638
Accession Number
NP_003847
Tag
C-Fc Tag
Type
Recombinant Proteins
Source
HEK293 cells
Field of Research
Innate Immunity
Buffer
Tris with Glycine, Arginine and NaCl, pH7.5
Shipping Conditions
Room Temp
Storage Conditions
Lyophilized Protein should be stored at -20˚ C or lower for long term storage. Upon reconstitution, working aliquots should be stored at -20˚ C or -70˚ C. Avoid repeated freeze-thaw cycles.
Calculated Molecular Weight
61.0 kDa
Applications Notes
This recombinant protein can be used for WB. For research use only.
NCBI Official Name
Interleukin 1 receptor-like 1
NCBI Organism
Homo sapiens
Background Reference 01
Tago K., et al., 2001, Biochem. Biophys. Res. Commun. 285:1377-1383.
Background Reference 02
Schmitz J., et al., 2005, Immunity 23:479-490.
Other Product Names
IL1RL1, DER4, FIT-1, IL33R, ST2, ST2L, ST2V, T1
Tested Applications
WB
Species
Human
Physical Properties
Lyophilized
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