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IFN gamma R1 Recombinant Protein

Product Specifications

Background

Interferon gamma receptor 1 (IFNGR1) encoded by the IFNGR1 gene, is a single-pass type 1 membrane protein which belongs to the type II cytokine receptor family. IFNGR1 is phosphorylated at Ser/Thr residues after translation. IFNGR1 is a receptor for interferon gamma, two receptors bind one interferon gama dimer. A genetic variation in IFNGR1 is associated with susceptibility to Helicobacter pylori infection. In addition, defects in IFNGR1 are a cause of mendelian susceptibility to mycobacterial disease, also known as familial disseminated atypical mycobacterial infection.

NCBI Gene ID

3459

Swiss Prot

P15260

Accession Number

P15260

Tag

C-6 His tag

Type

Recombinant Proteins

Source

Human Cells

Field of Research

Immunology, Signal Transduction, Other

Buffer

Supplied as a 0.2 um filtered solution of 20mM PB,150mM NaCl, pH7.4. It is not recommended to reconstitute to a concentration less than 100 ug/ml.

Shipping Conditions

Dry Ice

Product Datasheet

https://www.prosci-inc.com/?datasheet_sku=92-375

Calculated Molecular Weight

28.7 kD

Applications Notes

This recombinant protein can be used for biological assays. For research use only.

NCBI Official Name

Interferon gamma receptor 1

NCBI Organism

Homo sapiens

Other Product Names

Interferon gamma receptor 1, IFNGR1, CDw119, CD119

Species

Human

Protein ID

20149322

Physical Properties

Liquid

CAS Number

9000-83-3

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