IFN gamma R1 Recombinant Protein
Product Specifications
Background
Interferon gamma receptor 1 (IFNGR1) encoded by the IFNGR1 gene, is a single-pass type 1 membrane protein which belongs to the type II cytokine receptor family. IFNGR1 is phosphorylated at Ser/Thr residues after translation. IFNGR1 is a receptor for interferon gamma, two receptors bind one interferon gama dimer. A genetic variation in IFNGR1 is associated with susceptibility to Helicobacter pylori infection. In addition, defects in IFNGR1 are a cause of mendelian susceptibility to mycobacterial disease, also known as familial disseminated atypical mycobacterial infection.
CAS Number
9000-83-3
NCBI Gene ID
3459
Swiss Prot
P15260
Accession Number
P15260
Tag
C-6 His tag
Type
Recombinant Proteins
Source
Human Cells
Field of Research
Immunology, Signal Transduction, Other
Buffer
Supplied as a 0.2 um filtered solution of 20mM PB,150mM NaCl, pH7.4. It is not recommended to reconstitute to a concentration less than 100 ug/ml.
Shipping Conditions
Dry Ice
Calculated Molecular Weight
28.7 kD
Applications Notes
This recombinant protein can be used for biological assays. For research use only.
NCBI Official Name
Interferon gamma receptor 1
NCBI Organism
Homo sapiens
Other Product Names
Interferon gamma receptor 1, IFNGR1, CDw119, CD119
Species
Human
Protein ID
20149322
Physical Properties
Liquid
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